November 1, 2011 – A change in the kidney allocation policy dramatically reduced the racial disparity between the rates at which African Americans and whites receive deceased donor kidney transplants (DDKT), according to a study published in the November issue of the American Journal of Kidney Diseases, the official journal of the National Kidney Foundation (NKF).
In 2003, the United Network for Organ Sharing (UNOS) reversed a policy which assigned priority to potential kidney recipients who genetically matched up with the deceased donor in terms of HLA-B, an antigen found on the surface of cells that is involved in the immune response to foreign tissue and tends to be racially clustered. The preference given HLA-B matches, combined with a higher percentage of white donors, resulted in almost inevitable racial disparity in DDKT recipients.
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